Viability as occasional long distance tourer?

OK so:

I bought a 2018 R6 this past Summer, and while it's a lot of fun for a very specific purpose, it is also rough on my knees and wrists and really not much fun outside of ~hour of riding. I don't intend to get rid of it, but want something I can ride around town at a calmer pace and do some distance on.

For reference I've done some light interstate multi day touring on a Honda CBR 500R and found it to be perfectly fine riding 3 hours a day with the relatively upright position.

I'm going to do some more serious touring this coming Summer, probably from NY to NC. I'm hesitant to buy a dedicated touring bike because I don't tour regularly enough. However, the only naked bike I've ridden has been a MT-09 at a Yamaha ride event, so I don't have much experience with these types of bikes.

What's got me interested in the Duke 790 is:
-Great value.
-Amazing electronics package w/ lean sensitive ABS and TC.
-Lightweight.
-Powerful.
-Relatively upright and neutral riding position should be less physically stressful, especially vs a SS bike.
-Has a ton of "power parts" that should allow it to pseudo tour. Luggage, windscreens, USB power outlet, TPMS etc. seem to all be good additions.
-Can ride it hard and fast in the twisties and comfortably around town when I'm not touring, which would be most of the time.

Concerns:
-No cruise control. Could use a cramp buster probably, but not ideal.
-Engine possibly buzzy (causing numb hands on very long rides).
-Naked bike even with windscreen might be rough at 70-85 MPH highway for many hours at a time.

Can anyone shine some light on my concerns, esp. regarding engine buzz on handlebars/foot pegs, comfort of the seat, wind buffeting at higher speeds, and ergos? Anyone else think the bike could effectively be used to do a week long tour every once in a while?

Other contenders are Ninja 1000 and the Yamaha Tracer 900 GT, but those are much more touring dedicated and wouldn't be much fun outside that role.